CrossFit Exercise to Improve Glucose Control for Overweight and Obese Adults

Not Applicable

Completed

• Conditions: Hyperglycemia

• Registration Number: NCT02185872
• Lead Sponsor: Kansas State University

Brief Summary

The purpose of this study was to examine the differences in glucose control, fitness, and body composition between a standard aerobic and resistance exercise training program and a shorter-duration, high-intensity CrossFit training program in overweight and obese physically inactive adults.

Hypotheses:

1. Both groups would improve glucose control, with the CrossFit group improving significantly more than the aerobic and resistance training group.

2. Both groups would improve fitness, with the CrossFit group improving significantly more than the aerobic and resistance training group.

3. Both groups would demonstrate decreases in body fat percentage and fat mass and increases in lean body mass, with the CrossFit group improving significantly more than the aerobic and resistance training group.

Detailed Description

Overweight or obese participants will take part in an 8-week exercise intervention after clearance from a doctor, that is expected to improve glucose control, fitness (Eurofit and peak aerobic capacity), and body composition (body fat percentage, fat mass, and lean body mass). After stratification by age and body mass index, participants will be randomized to either a standard aerobic and resistance training exercise program or a relatively higher intensity, shorter duration CrossFit exercise program.

Study Timeline

• Study Start: 2012-02
• Primary Completion: 2012-05
• Study Completion: 2012-05
• Study First Submitted: 2014-07-03
• Study First Submitted QC: 2014-07-09
• Study First Posted: 2014-07-10
• Status Verified: 2015-03
• Last Update Submitted: 2015-03-30
• Last Update Posted: 2015-03-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

• body mass index (BMI) of 25 - < 40, physically inactive (i.e., not participating in any structured exercise programs for the past 2 months and not exceeding 30 total minutes of physical activity per week)

Exclusion Criteria

• current smoker, pregnant, taking blood glucose altering medications, heart disease, type 1 or 2 diabetes mellitus, total cholesterol 200 mg/dL or higher

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change from baseline in glucose control.	Baseline, Week 10	Fasting plasma glucose levels were taken after an overnight fast of at least 8 hours. An oral glucose tolerance test was conducted after ingestion of a 75g oral dextrose solution with finger sticks at 30, 45, and 60 minutes from time 0. The following equation was used to calculate glucose area under the curve which was the metric utilized to ascertain changes in glucose control: \[(Time 45 - Time 30) \* ½ (OGTT 30 + OGTT 45)\] + \[(Time 60 - Time 45) \* ½ (OGTT 60 + OGTT 45)\]

Secondary Outcome Measures

Name	Time	Method
Change from baseline in sit and reach	Baseline, Week 10	Eurofit protocol for sit and reach distance using flex tester box
Change from baseline in vertical jump	Baseline, Week 10	Eurofit protocol
Change from baseline in stork balance test	Baseline, Week 10
Change from baseline in pushups	Baseline, Week 10	Eurofit protocol; completed on feet or knees
Change from baseline in 40 meter dash	Baseline, Week 10	A handheld stopwatch was used to record time from the command "Go" until the participant crossed the line at 40 meters
Change from baseline in body composition	Baseline, Week 12	Dual X-ray absorptiometry scan was used to assess body fat percentage, lean body mass, and fat mass.
Change from baseline in situps	Baseline, Week 10	Eurofit protocol
Change from baseline in peak aerobic capacity	Baseline, Week 10	Modified Balke protocol
Change from baseline in standing broad jump	Baseline, Week 10	Eurofit protocol

Trial Locations

Locations (1)

Kansas State University; 🇺🇸 Manhattan, Kansas, United States