MedPath

A study about monitoring of circulating tumor cells in head and neck cancer

Not Applicable
Recruiting
Conditions
Neoplasms
Registration Number
KCT0006472
Lead Sponsor
Pusan National University Yangsan Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

1) 19 years old or older
2) Primary cancer site as the following head and neck cancer: oral cavity, oropharynx, larynx and hypopharynx, nasal cavity and paranasal sinus, nasopharynx
3) Histological diagnosis is squamous cell carcinoma (however, including cases with similar clinical course comparable to squamous cell carcinoma, for example, undifferentiated cancer)
4) Patients who have no distant metastasis
5) Patients whose curative treatment is determined as radiotherapy or chemoradiation
6) A person who signed written informed consent after voluntarily understanding the clinical research

Exclusion Criteria

1) Diagnosis of salivary gland cancer
2) Histologic type is not squamous cell carcinoma
3) Patients scheduled for radical surgery
4) Patients with distant metastasis
5) Patients who underwent major surgery requiring general anesthesia within 4 weeks of study registration
6) Those with a history of other malignancies within the past 3 years (excluding cured skin basal cell carcinoma, cervical epithelial cancer, superficial bladder cancer, and differentiated thyroid cancers)

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
CTC detection rate before starting CRT
Secondary Outcome Measures
NameTimeMethod
CTC detection rate in the end of CRT;CTC detection rate after 8-12 weeks after CRT completion;CTC detection rate in the detection of disease progression
© Copyright 2025. All Rights Reserved by MedPath