A randomized study of lactulose versus sennoside for prevention of bacterial peritonitis in peritoneal dialysis patients

Phase 3

Completed

• Conditions: Prevention of bacterial peritonitis in peritoneal dialysis patients; Peritoneal dialysis; Bacterial peritonitis; Lactulose; Sennoside

• Registration Number: TCTR20171012001
• Lead Sponsor: Renal Division, Department of Internal Medicine, Chiang Mai University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-10-12
• Study Completion: 2017-12-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Peritoneal dialysis patients who are
1. More than 15 years of age
2. Undergone peritoneal dialysis for more than 2 weeks

Exclusion Criteria

1. Inability to give informed consent
2. History of bacterial peritonitis more than 2 episodes
3. History of bacterial peritonitis 3 months before randomization
4. History of fungal peritonitis

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bacterial peritonitis 1 year Criteria to diagnose bacterial peritonitis

Secondary Outcome Measures

Name	Time	Method
Adverse effect from lactulose or sennoside 1 year Questions for the patient at every follow-up visit,Catheter removal 1 year Percentage of patients in each group who need to remove tenckhoff catheter