跳至主要内容
临床试验/NCT04674540
NCT04674540已完成不适用

Investigation on the Cognition and Implementation of Sedation and Analgesia in EICU Critically Ill Patients

Second Affiliated Hospital, School of Medicine, Zhejiang University1 个研究点 分布在 1 个国家目标入组 1,195 人开始时间: 2018年6月26日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
1,195
试验地点
1
主要终点
Cognition of Sedation and Analgesia

研究概览

简要总结

Sedation and analgesia is a very important part of the comprehensive treatment of critically ill patients. The comprehensive management strategy of sedation and analgesia in the Intensive Care Unit (ICU) and the control of infection, the application of antibiotics, and active recovery-are equally important. Effective sedation and analgesia assessment tools and reasonable comprehensive management strategies can not only improve patient comfort, reduce discomfort memory, but also reduce nursing workload and improve clinical outcomes. The "eCASH" theory proposed by Vincent et al. in 2016 further improved the comprehensive management strategy for sedation and analgesia. Its main contents are early analgesia to make patients comfortable, minimal sedatives and maximum humanitarian care. However, unreasonable sedation, especially early deep sedation, is closely related to the poor prognosis of patients. With the update of the ICU sedation and analgesia guidelines and the continuous progress of related research, ICU doctors have gradually deepened their understanding of sedation and analgesia. At present, the level of emergency ICU development in various regions of the country is uneven, and the implementation of sedation and analgesia may also vary greatly. Therefore, by investigating and understanding the implementation of emergency ICU or ICU sedation and analgesia in various regions of the country, you can indirectly understand the familiarity of medical staff with sedation and analgesia guidelines, and formulate corresponding strategies for specific situations, which may help improve critical illness. The level of sedation and analgesia of the patient improves the treatment effect.

So far, there are few domestic research reports on the implementation of sedation and analgesia in critical patients, especially the data in the emergency ICU. This study intends to investigate the implementation status of sedation and analgesia in critically ill patients in ICU, to understand the familiarity of medical staff with sedation and analgesia guidelines, and provide a basis for further measures.

详细描述

Part 1: Cognitive survey

Participants: emergency and critical illness medical staff (doctors and nurses) of participating units. The number of medical staff in each unit is at least 12, among which doctors and nurses are ≥6 (the ratio is ≥3 for elementary level and ≥3 for intermediate and above).

Investigate awareness of sedation and analgesia guidelines.

Part 2: Current status of sedation and analgesia

Participants: patients older than 18 years old in the ICU of the participating unit.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Multiple intensive care units (ICU) and emergency intensive care units (EICU) in China
  • Patients older than 18 years in the ICU/EICU

排除标准

  • 未提供

结局指标

主要结局

Cognition of Sedation and Analgesia

时间窗: 1 day

Awareness of sedation and analgesia guidelines. The questionnaire involves 20 questions about the main principles and knowledge of ICU sedation and analgesia treatment.

Analgesia evaluation: The digital pain scoring method

时间窗: 1 day

Analgesia evaluation: The digital pain scoring method is used for awake patients (score from 0 to 10);

Analgesia evaluation: Critical-Care Pain Observation Tool

时间窗: 1 day

Analgesia evaluation: non-conscious patients should use the Critical-Care Pain Observation Tool (CPOT, score from 0 to 8).

Sedation assessment: Richmond Agitation and Sedation Scale

时间窗: 1 day

Sedation assessment: Richmond Agitation and Sedation Scale (RASS, score from -5 to 4) for sedation assessment.

Analgesia evaluation-Confusion Assessment Method of the Intensive Care Unit

时间窗: 1 day

Evaluation of delirium: Confusion Assessment Method of the Intensive Care Unit (CAM-ICU) for delirium evaluation.

次要结局

  • General information of patients-APACHE II(1 day)
  • General information of patients-gender(1 day)
  • General information of patients-age(1 day)
  • General information of patients-BMI(1 day)
  • General information of patients-length of stay in ICU(1 day)

研究者

发起方
Second Affiliated Hospital, School of Medicine, Zhejiang University
申办方类型
Other
责任方
Sponsor

研究点 (1)

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