Retrospective Case-control Study of Central Line Botriomycoma in Children on Home Parenteral Nutrition: Epidemiology, Risk Factors, Treatments
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- Appearance of Botryomycoma
研究概览
简要总结
Botriomycomas are frequent benign tumors in children. Their appearance on the central catheter orifice is a known event in clinical practice, but one that has been little studied. This lesion could lead to changes in pathways and an increase in the number of sepsis events, which would promote thrombosis and thus depletion of venous capital in patients who have been dependent on a central line for many years.
This study is a pilot study which will enable us to better identify the risk factors for the development of such a tumour, and to take stock of the different treatments used and their respective efficacy.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •home parenteral nutrition patients
- •never diagnosed with an episode of botriomycoma on their central line
- •0 to 18 years of age at diagnosis
排除标准
- •Botriomycoma more than 10 years old at time of data collection (or lack of data)
- •Patient over 18 years of age
- •Not on home parenteral nutrition patients
结局指标
主要结局
Appearance of Botryomycoma
时间窗: From first diagnosis through a follow-up period of 2 years.
genetic characteristics (origin, phototype), local factors (mechanical, infectious), and general factors (history of sepsis).
Recurrence of Botryomycoma
时间窗: From first diagnosis through a follow-up period of 2 years.
analyze risk factors for recurrence and evolution under different treatments.
次要结局
未报告次要终点