Genmab
Clinical Trials
242
Trial Phases
4 Phases
Drug Approvals
1
Drug Approvals
Clinical Trials
Distribution across different clinical trial phases (187 trials with phase data)• Click on a phase to view related trials
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
- Conditions
- Endometrial CancerRecurrent or Progressive Endometrial Cancer
- Interventions
- Drug: IC
- First Posted Date
- 2025-09-10
- Last Posted Date
- 2025-09-15
- Lead Sponsor
- Genmab
- Target Recruit Count
- 544
- Registration Number
- NCT07166094
Study of the Effectiveness and Safety of Acasunlimab Alone and With Pembrolizumab to Treat Advanced Melanoma of the Skin That Has Returned After Treatment With an Approved Checkpoint Inhibitor Therapy (ABBIL1TY MELANOMA-07)
- Conditions
- Cutaneous MelanomaRelapsed/Refractory, Locally Advanced Unresectable Melanoma (Stage IIIB, IIIC, or IIID)Metastatic Cutaneous Melanoma (Stage IV)
- Interventions
- First Posted Date
- 2025-05-22
- Last Posted Date
- 2025-09-03
- Lead Sponsor
- Genmab
- Target Recruit Count
- 90
- Registration Number
- NCT06984328
- Locations
- 🇺🇸
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
🇵🇷Pan American Center for Oncology Trials, LLC, San Juan, Puerto Rico
A First-in-Human Trial of Safety and Efficacy of GEN1078 in Participants With Solid Tumors
- First Posted Date
- 2025-01-13
- Last Posted Date
- 2025-07-15
- Lead Sponsor
- Genmab
- Target Recruit Count
- 3
- Registration Number
- NCT06771921
- Locations
- 🇪🇸
Hospital Universitari Vall d'Hebron, Barcelona, Spain
🇪🇸NEXT Oncology Madrid, Madrid, Spain
🇩🇰Righshospitalet (Copenhagen University Hospital), Copenhagen, Denmark
A Phase 1/2 Study of GEN1286 in Patients With Advanced Solid Tumors
- First Posted Date
- 2024-11-12
- Last Posted Date
- 2025-09-03
- Lead Sponsor
- Genmab
- Target Recruit Count
- 260
- Registration Number
- NCT06685068
- Locations
- 🇺🇸
START Midwest, Grand Rapids, Michigan, United States
🇺🇸START San Antonio, San Antonio, Texas, United States
🇺🇸START Mountain Region, West Valley City, Utah, United States
Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)
- Conditions
- PD-L1-positive Metastatic NSCLC
- Interventions
- First Posted Date
- 2024-10-10
- Last Posted Date
- 2025-08-07
- Lead Sponsor
- Genmab
- Target Recruit Count
- 702
- Registration Number
- NCT06635824
- Locations
- 🇺🇸
Usc Norris Comprehensive Cancer Center, Los Angeles, California, United States
🇺🇸Kaiser Permanente Vallejo Medical Center, Vallejo, California, United States
🇺🇸Ocala Oncology Center P.L., Ocala, Florida, United States
- Prev
- 1
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- 11
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News
Lundbeck Advances Innovative Phase 3 Trial Design for Amlenetug in Multiple System Atrophy
Lundbeck will present details of its Phase 3 MASCOT trial for amlenetug, a first-in-class monoclonal antibody targeting α-synuclein aggregation in Multiple System Atrophy patients.
Biopharma M&A Activity Surges in Q3 2025 with $55.7 Billion in Acquisitions
The biopharmaceutical sector experienced a significant surge in high-value acquisitions during Q3 2025, with four of the year's five largest deals occurring in the past four months.
Genmab Announces $5.2 Billion Acquisition of Merus to Expand Late-Stage Oncology Pipeline
Genmab will acquire Merus for $97.00 per share, representing a 41% premium and totaling approximately $5.2 billion in the largest deal in Genmab's history.
Follicular Lymphoma Market Poised for 6% CAGR Growth Through 2034 as Novel Therapies Advance
The follicular lymphoma market is projected to grow at a 6% CAGR during 2025-2034, driven by increased disease awareness and rising number of clinical trials focused on this slow-growing B-cell malignancy.
Genmab and BioNTech Advance Two Phase 1/2 Cancer Trials Testing Novel Antibody Therapies
Genmab and BioNTech are conducting two separate clinical trials evaluating novel antibody therapies for solid tumors, including GEN1055 monotherapy and combination treatments.
Genmab Advances Two Phase 3 and Phase 2 Trials Testing Acasunlimab Combinations in Lung Cancer and Melanoma
Genmab is conducting a Phase 3 trial evaluating acasunlimab combined with pembrolizumab versus docetaxel in PD-L1 positive metastatic non-small cell lung cancer patients who progressed after prior PD-1/PD-L1 inhibitor and platinum-containing chemotherapy.
Commit Biologics Forms Scientific Advisory Board to Advance Complement-Based Cancer and Autoimmune Therapies
Commit Biologics has established a Scientific Advisory Board co-chaired by antibody expert Janine Schuurman and CEO Mikkel Wandahl Pedersen to guide development of its BiCE™ complement activation platform.
Epcoritamab Demonstrates Durable 3-Year Remissions in Relapsed/Refractory Large B-Cell Lymphoma
Epcoritamab-bysp achieved durable complete responses in patients with relapsed/refractory large B-cell lymphoma, with 96% of complete responders at 2 years maintaining remission at 3 years.
World ADC San Diego Conference Highlights Growing Industry Focus on Antibody-Drug Conjugates
The 15th World ADC San Diego conference (November 4-7, 2024) represents the industry's largest and most comprehensive ADC-focused forum, featuring 120+ speakers across six development tracks.
Genmab to Present Extensive Epcoritamab Clinical Data at 2025 European Hematology Association Congress
Genmab will showcase 14 abstracts evaluating epcoritamab, their subcutaneously administered T-cell engaging bispecific antibody, across multiple lymphoma settings at the 2025 EHA Congress in Milan.