Seasonal Variation of Ambulatory Blood Pressure

Completed

• Conditions: Hypertension

• Registration Number: NCT01119755
• Lead Sponsor: University of Athens

Brief Summary

This is a prospective study to evaluate the change in 24 hour ambulatory blood pressure during winter and summer in well controlled treated hypertensives.

Detailed Description

Two 24hour ambulatory blood pressure monitorings, 4 to 6 months apart, will be performed on hypertensive subjects on a stable antihypertensive drug therapy for at least 4 weeks.

The correlation of weather and temperature with the 24hour ambulatory blood pressure monitoring will be explored.

Study Timeline

• Study Start: 2010-01
• Study First Submitted: 2010-04-21
• Study First Submitted QC: 2010-05-06
• Study First Posted: 2010-05-10
• Primary Completion: 2011-08
• Study Completion: 2011-08
• Status Verified: 2011-12
• Results First Submitted: 2011-12-08
• Results First Submitted QC: 2011-12-08
• Last Update Submitted: 2011-12-08
• Results First Posted: 2012-01-23
• Last Update Posted: 2012-01-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Age > 40 yrs
• Treated hypertension on stable treatment for at least 8 weeks
• Average home blood pressure (at least 5 days, 20 readings) < 130/80 mmHg

Exclusion Criteria

• Congestive heart failure
• Use of loop diuretics

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean Difference of Systolic Daytime Ambulatory Blood Pressure Between Summer and Winter.	1 year	Mean difference of systolic daytime ambulatory blood pressure measurement during summer and winter period
Mean Difference of Diastolic Daytime Ambulatory Blood Pressure Between Summer and Winter	1 year	Mean Difference of Diastolic Daytime Ambulatory Blood Pressure Measurement During Summer and Winter Period
Mean Difference of Systolic Night-time Ambulatory Blood Pressure Between Summer and Winter	1 year	Mean difference of systolic night-time ambulatory blood pressure measurement during summer and winter period
Mean Difference of Diastolic Night-time Ambulatory Blood Pressure Between Summer and Winter	1 year

Secondary Outcome Measures

Name	Time	Method
Mean Difference of Systolic Clinic Blood Pressure Between Summer and Winter	1 year
Mean Difference of Diastolic Clinic Blood Pressure Between Summer and Winter	1 year
Mean Difference of Systolic Home Blood Pressure Between Summer and Winter	1 year
Mean Difference of Diastolic Home Blood Pressure Between Summer and Winter	1 year

Trial Locations

Locations (1)

Hypertension Center, Third Department of Medicine, University of Athens, Greece; 🇬🇷 Athens, Greece