Central Blood Pressure in Adolescents and Young Adults

• Conditions: Healthy; Hypertension

• Registration Number: NCT02222077
• Lead Sponsor: University of Athens

Brief Summary

This study aims to investigate in adolescents and young adults:

* the 24h diurnal variation of ambulatory central blood pressure

* the association of central compared to peripheral blood pressure with indices of asymptomatic target-organ damage

Detailed Description

Not available

Study Timeline

• Study Start: 2014-07
• Study First Submitted: 2014-08-15
• Study First Submitted QC: 2014-08-19
• Study First Posted: 2014-08-21
• Status Verified: 2017-09
• Last Update Submitted: 2017-09-13
• Last Update Posted: 2017-09-14
• Primary Completion: 2018-02
• Study Completion: 2018-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Adolescents and young adults (age range 12-25 years)

Exclusion Criteria

• Subjects with any acute or significant chronic disease, with evidence of secondary hypertension, or on regular drug treatment will be excluded

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation coefficients (r) between 24h ambulatory central blood pressure and indices of target-organ damage	Assessment of each individual will require up to 3 days	Correlation coefficients (r) will be determined for the relationship between central blood pressure and indices of target-organ damage (left ventricular mass index, carotid intima-media thickness, pulse wave velocity). Also, these coefficients will be compared with z-statistic with the respective ones for the peripheral blood pressure.

Trial Locations

Locations (1)

Hypertension Center, 3rd University Department of Medicine, Sotiria Hospital; 🇬🇷 Athens, Attica, Greece