跳至主要内容
临床试验/ISRCTN25173360
ISRCTN25173360进行中(未招募)未知

Preventing Ovarian Cancer through early Excision of Tubes and late Ovarian Removal

Queen Mary University of London0 个研究点目标入组 1,000 人开始时间: 2018年6月14日最近更新:
适应症

试验速览

阶段
未知
状态
进行中(未招募)
入组人数
1,000

研究概览

简要总结

2020 protocol in https://pubmed.ncbi.nlm.nih.gov/32907814/ (added 11/09/2020)

研究设计

研究类型
Interventional

入排标准

性别
Female

入选标准

  • 1. Women at increased risk of ovarian cancer: BRCA1/BRCA2 mutation carriers; RAD51C/RAD51D/BRIP1 mutation carriers; strong family history of breast and ovarian cancer or ovarian cancer alone.
  • 2. Premenopausal
  • 3. Aged =30 years.
  • 4. Completed family (for surgical arms)

排除标准

  • 1. Previous bilateral-salpingectomy or bilateral-oophorectomy.
  • 2. Postmenopausal (amenorrhoea =1year (uterus in situ) / FSH >40).
  • 3. Previous tubal/ovarian/peritoneal malignancy
  • 4. <12 months post cancer treatment
  • 5. Pregnancy
  • 6. Clinical suspicion of tubal/ovarian cancer at baseline
  • 7. Inability to provide informed consent

研究者

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