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Effect of Turmeric on Diabetic Nephropathy

Not Applicable
Completed
Conditions
Proteinuria
Diabetic Nephropathy
Interventions
Drug: Angiotensin-converting enzyme (ACE) inhibitor + Angiotensin-II type 1 receptor (ATI) blocker
Registration Number
NCT01015937
Lead Sponsor
Shaheed Faghihi Hospital
Brief Summary

The purpose of this study is to investigate whether turmeric is effective in improvement of diabetic nephropathy and in decrease in the amount of proteinuria and cytokine levels.

Detailed Description

Diabetic nephropathy is leading cause of ESRF that many therapy recommended for it. In this study, we investigate effect of turmeric on diabetic nephropathy, thus we selected diabetic nephropathy patients and divided them into 2 groups. One group received turmeric + ACE inhibitor + Angiotensin II receptor blocker (ARB) and the second group received only ACE inhibitor + ARB.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
50
Inclusion Criteria
  • diabetic nephropathy
  • more than 300 mg proteinuria/day
  • age more than 18 years old
Exclusion Criteria
  • DM type 1

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
ACE inhibitor + ATI blockerAngiotensin-converting enzyme (ACE) inhibitor + Angiotensin-II type 1 receptor (ATI) blockerdiabetic nephropathy more than 300 mg/day proteinuria
TurmericTurmeric extractdiabetic nephropathy patient more than 300 mg/proteinuria
ACE inhibitor + ATI blockerTurmeric extractdiabetic nephropathy more than 300 mg/day proteinuria
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Clinic

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Shiraz, Fars, Iran, Islamic Republic of

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