Glycemic control and metabolic parameters after a very low caloric diet in hospital personnel with type 2 diabetes mellitus: a pilot study
Phase 3
Completed
- Conditions
- Diabetes mellitus type 2ObesityDietary interventionVery low caloric dietDiabetes mellitus type 2ObesityQuality of life
- Registration Number
- TCTR20150930002
- Lead Sponsor
- Quality Improvement Fund, King Chulalongkorn Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
1. Personnel of King Chulalongkorn Memorial Hospital with type 2 diabetes
2. Age 20-60 years
3. Glycated hemoglobin level > 6.5%
4. Diabetes duration < 10 years
5. BMI> 23 kg/m2
Exclusion Criteria
1. Patients were treated with TZD, GLP-1 agonist or insulin treatment.
2. Serum creatinine >1.5 mg/dL
3. Serum ALT > 2.5 folds above UNL
4. Serum C-peptide <1 ng/ml
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method DM remission 8 and 12 weeks 75 gm OGTT
- Secondary Outcome Measures
Name Time Method metabolic parameters, body composition, quality of life 0, 8 and 12 weeks lipid profile, body composition, quality of life score