A role of P.gingivalis and Acetaldehyde in barrier dysfunction of gastric mucosa after H.pylori eradicatio
- Conditions
- Gastric cancer after H.pylori eradication
- Registration Number
- JPRN-UMIN000034376
- Lead Sponsor
- Tohoku University
- Brief Summary
There is no difference in decrease of mucosal impedance of the background mucosa of gastric cancer between the stimulation with Pg.LPS and that with Pg.LPS + acetaldehyde.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 36
Not provided
1) patients younger than 20 years old or older than 85 years old; 2) patients with a history of chemotherapy, radiotherapy or upper abdominal surgery; 3) patients taking nonsteroidal anti-inflammatory drugs, antibiotics, or any acid secretion inhibitors; 4) patients with serious medical conditions; 5) patients suffering from mental disorders; 6) patients who might be pregnant; 7) patients with inappropriate specimens; 8) patients with contraindication for endoscopic biopsy or gastrin injection; and 9) patients who refused to participate in this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mucosal damage of atrophic mucosa by the stimulation of P.gingivalis LPS or LPS and acetaldehyde
- Secondary Outcome Measures
Name Time Method
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