Implementation of pharmacokinetic (PK)-guided dosing of DDAVP and VWF-containing concentrates in von Willebrand disease and low VWF
Recruiting
- Conditions
- Von Willebrand disease, pharmacokinetics, treatment, bleeding, surgery
- Registration Number
- NL-OMON20178
- Lead Sponsor
- Erasmus University Medical Center - Sophia Children's Hospital, University Medical Center Rotterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 123
Inclusion Criteria
No minimum or maximum age at inclusion date;
-Hemorrhagic symptoms or a family history of von Willebrand disease or low VWF with historically lowest levels of VWF:Ag and/or VWF:Act and/or VWF:Cb <0.60 IU/ml and/or FVIII <0.40 IU/ml (only in type 2N);
Exclusion Criteria
-Any other known hemostatic abnormalities;
-Acquired VWD;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method