Effects of acute elevation of circulating fatty acids on skeletal muscle lipid accumulation in healthy lean young me

Completed

• Conditions: Skeletal muscle lipid metabolism; Skeletal muscle metabolism; The metabolic process of the skeletal muscle

• Registration Number: NL-OMON38652
• Lead Sponsor: niversiteit Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 32

Inclusion Criteria

- Male sex
- Age 18-30 years
- Lean, BMI 18-25 kg/m2
- Healthy
- Stable dietary habits
- No medication use

Exclusion Criteria

- Female sex
- Engagement in programmed exercise > 2 hours total per week
- Cardiac problems, such as angina pectoris, cardiac infarction and arrhythmias
- First degree relatives with type 2 diabetes mellitus
- Any medical condition requiring treatment and/or medication use
- Unstable body weight (weight gain or loss > 3 kg in the past three months)
- Participation in another biomedical study within 1 month prior to the screening visit
- Subjects, who do not want to be informed about unexpected medical findings, or do not wish that their treating physician is informed, cannot participate in the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Skeletal muscle lipid content before, directly after exercise and 4 h post<br /><br>exercise (determined from muscle biopsies) with or without glucose<br /><br>supplementation. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>