Comparison of one day with four days antibiotic use in cancer patients
- Conditions
- Health Condition 1: null- The patients will be those who will be undergoing clean, contaminated, planned cancer surgeries of abdomen
- Registration Number
- CTRI/2018/06/014344
- Lead Sponsor
- Basavatarakam IndoAmerican Cancer Hospital and Research Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Clean contaminated oncological surgeries i.e., gastrointestinal, gynaecological and urological surgeries
2.Age group 15 to 75 years
1.Patients less than 15 years old (pediatric age).
2.Those with known allergy to cephalosporin antibiotics.
3.Those with any infection within the prior 2 weeks.
4.Those patient whose White Blood Cell (WBC) count is less than 3000 cells per cubic millimeter of blood /WBC counts more than 12000/mm3 .
5.Any patient who develops infection after the surgery will be recorded as an event and removed from the study and will be treated as per as standard antibiotic protocol.
6.Cases in which intraoperatively a major breach of sterility with gross contamination and uncontrolled spillage from gastrointestinal track has occurred.
7.Contaminated and infected surgeries as per CDC definition.
8.Clean surgeries as per CDC definition.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome is to show that the one dose-prophylaxis was not inferior to the multiple-dose prophylaxis in terms of the overall incidence of surgical site infections.Timepoint: 30 days
- Secondary Outcome Measures
Name Time Method To determine the factors influencing the risk of surgical site infectionTimepoint: 30 days