Without antibiotic prophylaxis in children with mild vesicoureteral reflux (grade 0-2) after a first urinary tract infection. : A multicenter trial.

Not Applicable

• Conditions: rinary tract infection

• Registration Number: JPRN-UMIN000001806
• Lead Sponsor: Tokyo Metropolitan Children's Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-03-27
• Study Completion: 2015-08-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up continuing
• Sex: All
• Target Recruitment: 130

Inclusion Criteria

Not provided

Exclusion Criteria

1) Gestational age < 37 weeks. 2) Weight at birth < 2000g. 3) Complex urologic malformations. 4) Neurogenic bladder. 5) Hydronephrosis or ureteral dilation over grade 3 according to SFU classification. 6) Phimosis and ballooning at urination. 7) Previous episode of UTI. 8) Using antibiotic prophylaxis for another infection. 9) Renal dysfunction at recovery phase of UTI. (By EIA method, <1year old: sCr >= 0.4, >=1year old: sCr >= 0.5) 10) Hypertension at recovery phase of UTI. 11) Liver dysfunction at recovery phase of UTI. (AST or ALT exceed over 2.5 times the upper limit of normal). 12) Known to be immunocompromised status. 13) Intractable UTI (duration of fever >= 7days after beginning of antibiotics). 14) Complicated septic shock or DIC. 15) Judged inappropriate for this study by the physician.

Study & Design

• Study Type: Interventional
• Study Design: Not specified