Cognitive Impairment in Diabetes

Completed

Conditions: adult onset diabetes mellitus
type 2 diabetes
10012653
10012272

Registration Number: NL-OMON39732

Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 228

Inclusion Criteria

Diagnosis of type 2 diabetes and aged 70 years or older

Exclusion Criteria

- Patients with a previous diagnosis of cognitive problems or dementia
- Patients unable or unwilling to give written informed consent
- Not capable of writing and reading in Dutch

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study outcome is a diagnosis of cognitive impairment, defined as<br /><br>either MCI or dementia, regardless of the underlying etiology. The diagnosis<br /><br>will be established at the memory clinic at a multidisciplinary team meeting<br /><br>with a rigorous standardized work-up and according to internationally accepted<br /><br>diagnostic criteria. With this outcome we can calculate the accuracy of the<br /><br>screening instruments and the GP evaluation.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secundary outcome of the study will be a a detailed characterisation (cognitive<br /><br>profile, brain MRI, diagnosis) of a population based sample of patients with<br /><br>T2DM and cognitive impairment. Furthermore, we will examine the effect of the<br /><br>diagnostic procedure on diabetes care and patients* quality of life six and<br /><br>twenty-four months after a diagnosis of cognitive dysfunction.</p><br>