NCT00806715已完成不适用
Impact of Iron Overload in Pediatric Patients Undergoing Stem Cell Transplantation
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 38
- 试验地点
- 1
- 主要终点
- Hepatic iron content as measured by R2 MRI.
研究概览
简要总结
The goal of this study is to examine the impact of iron overload in patients undergoing a bone marrow transplant. We believe that the iron status in these patients is associated with complications for transplant survivors. We will examine the iron status in these patients by MRI and by screening for mutations in genes known to cause iron overload. We will also determine the levels of hepcidin (a hormone produced in the liver that appears to regulate iron homeostasis) from blood and urine.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 5 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Hepatic iron content as measured by R2 MRI.
时间窗: Pre-HSCT and Day 100
次要结局
- Genetic determinants of iron overload- HFE status.(Pre-HSCT)
研究者
Deborah Chirnomas
Instructor
Boston Children's Hospital
研究点 (1)
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