Comparison between Pregabalin and Sertraline for treatment of itching in kidney failure

Not Applicable

• Conditions: end stage renal disease.; End stage renal disease; N18.6

• Registration Number: IRCT20240208060941N1
• Lead Sponsor: Pak Emirates Military Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 March 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

Patients from both genders greater than 18 years of age
Patients on twice weekly hemodialysis for at least 6 months
Patients having uremic pruritus for more than 6 weeks

Exclusion Criteria

Patients with dermatological or systemic diseases associated with pruritis (such as acute hepatitis, chronic liver disease, pregnancy, and hypothyroidism)
Patients with mental health issues affecting their ability to respond to the 5-D Itch Scale (such as psychosis, obsessive-compulsive disorder, or substance abuse)
Patients on thrice-a-week haemodialysis schedule
Not consenting to participate

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in severity of pruritis. Timepoint: 6 weeks post initiation of treatment. Method of measurement: The 5-D Itch Scale (Urdu version).