Melatonin ischemic stroke

Phase 2

Recruiting

• Conditions: Cerebellar stroke syndrome.; Cerebellar stroke syndrome; G46.4

• Registration Number: IRCT20190804044429N10
• Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Adults over the age of 18 and diagnose with acute ischemic stroke according to brain CT scan findings
NIHSS more than 4

Exclusion Criteria

Hemorrhagic stroke
Lacunar infarct
TIA
NIHSS more than 25
Pregnancy
Lactation
Severe hepatic insufficiency
History of apnea

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Glutathione serum level. Timepoint: days 0 and 5th of the study. Method of measurement: Spectroscopy.;Antioxidant serum levels. Timepoint: at days 0 and 5th of the study. Method of measurement: Spectroscopy.

Secondary Outcome Measures

Name	Time	Method
Disability following stroke. Timepoint: At days 0, discharge and month three of the study. Method of measurement: According to mRS.;Tolerability of melatonin. Timepoint: During the study period. Method of measurement: History taking.