IRCT201107187049N1已完成3 期
An assessment of effects of melatonin on metabolic effects of olanzapine in patients with schizophrenia
Guilan University of Medical ScienceS0 个研究点目标入组 40 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 65 years（—）
- 性别
- All
入选标准
- •Inclusion Criteria: age 18-65 year?diagnosis of schizophrenia based on DSM-IV-TR? capability to take drugs at 9.00 pm
- •Exclusion criteria: married women who are at reproductive age; history of drug abuse or dependence in the recent 30 days;history of taking olanzapine in the recent 3 months;history of allergy or intolerance to olanzapine; history of significant head trauma ( causing loss of concioussness more than 5 minutes or neurolgical or cognitive sequels);liver, kidney, cerebrovascular or cardiovascular disease;diabetes;metabolic syndrome; cancer ;using antiepileptic , antihypertensive or anticoagulant or anti-platelet drugs; using inhibitors or stimulants of hepatic isoenzymes that metabolize melatonin or olanzapine (e.g. omeprazole. rifampin, fluvuxamine, ciprofloxacin, carbamazepine, and modafinil) ; patients develop diabetes; acidosis; severe anticholinergic side effects; delirium or need for administration of another drug
排除标准
- 未提供
研究者
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