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Improving the experience of physical activity in people with severe lung disease using dietary nitrate supplementation with beetroot juice

Not Applicable
Conditions
Chronic obstructive pulmonary disease
Respiratory
Registration Number
ISRCTN12474100
Lead Sponsor
Imperial College London
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Ongoing
Sex
All
Target Recruitment
102
Inclusion Criteria

1. Adults aged 18 years and over
2. Diagnosis of COPD
3. Under care of home oxygen service
4. Documented oxygen assessment meeting NICE criteria:
4.1. PaO2< 7.3 or < 8 if pulmonary hypertension
4.2. Increase in exercise capacity if ambulatory oxygen only

Exclusion Criteria

1. Inability to consent
2. Systolic blood pressure below 120mmHg
3. Exacerbation within the last four weeks
4. Use of nitrate-based medication

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Experience of difficulty with physical activity measured using the difficulty domain of the clinic visit PROactive COPD tool, c-PPAC, at baseline and 3 months
Secondary Outcome Measures
NameTimeMethod
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