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Clinical Trials/NCT03377205
NCT03377205
Active, Not Recruiting
N/A

Intramedullary Nailing Versus Plate Fixation of Ankle Fractures.

Oslo University Hospital1 site in 1 country120 target enrollmentJune 2016
ConditionsAnkle Fractures

Overview

Phase
N/A
Intervention
Not specified
Conditions
Ankle Fractures
Sponsor
Oslo University Hospital
Enrollment
120
Locations
1
Primary Endpoint
American Orthopaedic Foot and Ankle Society (AOFAS) score
Status
Active, Not Recruiting
Last Updated
2 years ago

Overview

Brief Summary

The purpose of this study is to make a survey of functional outcome, radiological outcome and complication rate after intramedullary nailing (IMN) and plate fixation of Weber B ankle fractures in elderly patients, and contribute in choosing the best surgical method for these ankle fractures.

Detailed Description

Open reduction and internal fixation (ORIF) is the gold standard treatment for unstable Weber B fractures, using compression screws and a neutralization plate. In the elderly, pre-existing co-morbidities, osteoporosis and poor skin conditions may give a high complication rate, including wound complications, symptomatic hardware and hardware failure. Due to concerns with complications related to ORIF, the technique with intramedullary fixation has been introduced. This method may simplify the management when poor skin conditions and osteoporotic bone, and has the potential to reduce the risk of soft tissue and hardware complications. Previous studies have showed that intramedullary fixation is probably the best choice for treating unstable ankle fractures in elderly patients, but more studies are needed to conclude the superiority to standard plate fixation.

Registry
clinicaltrials.gov
Start Date
June 2016
End Date
January 2026
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Oslo University Hospital
Responsible Party
Principal Investigator
Principal Investigator

Elisabeth Ellingsen Husebye

Principal investigator

Oslo University Hospital

Eligibility Criteria

Inclusion Criteria

  • Acute unstable Weber B fracture (unimalleolar, bimalleolar or trimalleolar fractures).
  • Operable with both methods of surgery within 3 weeks after injury.
  • Men and women ≥ 60 yoa.

Exclusion Criteria

  • Prior injury or pathology with reduced ankle function.
  • Other acute foot/ankle/leg injury that will affect ankle function.
  • Fracture of the posterior malleolus that need fixation.
  • Injury / pathology that may affect rehabilitation.
  • Open fracture.
  • Inoperable patient.
  • Dementia (MMSE score ≤ 24 points), reduced competent to consent, not able to express himself/herself in Norwegian or English.

Outcomes

Primary Outcomes

American Orthopaedic Foot and Ankle Society (AOFAS) score

Time Frame: 5 years

Functional outcome as assessed by AOFAS score (0-100)

Secondary Outcomes

  • Olerud and Molander Score (OMS)(5 years)
  • Visual analogue scale (VAS)(5 years)
  • Infection(3 months)
  • Malunion as assessed by CT scans(5 years)
  • Nonunion as assessed by CT scans(5 years)
  • Manchester-Oxford Foot questionnaire (MOxFQ)(5 years)
  • EuroQol-5d (Eq-5d)(5 years)
  • Osteoarthritis as assessed by CT scans(5 years)
  • Fracture reduction as assessed by CT scans(3 months)
  • Delayed wound healing(3 months)
  • Other complications(5 years)

Study Sites (1)

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