To compare vasodilatory effect of desflurane vs sevoflurane using perfusion index as a measure
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/05/052699
- Lead Sponsor
- Dayanand Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
sixty adults of either sex, age group (18yr-65yr) belonging to the American Society of Anaesthesiologist (ASA) Physical status I and II adults scheduled for elective surgery under GA
1.Receiving any medications that may affect vascular tone (eg vasoactive drugs, such as calcium channel blockers or angiotensin receptor blockers)
2.Cardiovascular or peripheral vascular disease (e.g. Diabetic vasculopathy or Raynaudâ??s disease)
3.Medications that may affect sympathetic or parasympathetic tone(e.g. beta blockers or anticholinergics)
4.Diabetes mellitus
5.Any neurological or psychiatric diseases, including history of, or treatment for, substance abuse, anxiety, or depression.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Perfusion index will be the primary outcome for the study.Timepoint: Baseline Perfusion index will be noted and then continuously recorded every minute for 20 min ,after induction of anaesthesia
- Secondary Outcome Measures
Name Time Method To compare heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure. <br/ ><br> <br/ ><br>Timepoint: Baseline HR, PI, SBP, DBP and MAP will be noted and then continuously recorded every minute for 20 min ,after induction of anaesthesia. <br/ ><br> <br/ ><br>