To study the cardiovasculair effects of vasodilatation by nifedipine (Adalat gastrointestinal therapeutic system) with or without plasma volume expansion with Voluven (colloid) in women with preeclampsia

Phase 1

• Conditions: preeclampsia

• Registration Number: EUCTR2006-003143-23-NL
• Lead Sponsor: St Radboud UMC

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2006-07-05
• Study Completion: 2013-01-01
• Last Update Posted: 8 August 2022

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: Female
• Target Recruitment: 22

Inclusion Criteria

preeclampsia, gestational age 24- 34 weeks, singleton pregnancy
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years)
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years)
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

known allergy to nifedipine, known cardiovasculair or renal- or liverpathology, previous treatment with antihypertensives or tocolytics, foetal distress necessitating delivery in less than 48 uur, imminent eclampsia, no informed consent from the patient or the doctor treating the patient, multiple pregnancy, unable to take tablets

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified