Evaluation of Periodontal Diseases and Obesity in Women

Not Applicable

Completed

• Conditions: Periodontal Diseases; Obesity
• Interventions: Other: Exercise

• Registration Number: NCT03442920
• Lead Sponsor: Kocaeli University

Brief Summary

The aim of this study was to evaluate the effect of obesity and exercise on periodontal and biochemical parameters \[serum, saliva and gingival crevicular fluid (GCF) adipokines (interleukin-1β, tumor necrosis factor-α, leptin, resistin and adiponectin)\].

Detailed Description

It is thought that adipokines may play a role on periodontal disease in obese subjects, periodontal disease may also aggravate the existing systemic disease by changing the inflammatory parameters in the body. The aim of this study was to evaluate the effect of obesity and exercise on periodontal and biochemical parameters \[serum, saliva and gingival crevicular fluid (GCF) adipokines (interleukin-1β, tumor necrosis factor-α, leptin, resistin and adiponectin)\].

Study Timeline

• Study Start: 2014-12-29
• Primary Completion: 2015-06-11
• Study Completion: 2016-01-10
• Status Verified: 2018-02
• Study First Submitted: 2018-02-09
• Study First Submitted QC: 2018-02-21
• Last Update Submitted: 2018-02-21
• Study First Posted: 2018-02-22
• Last Update Posted: 2018-02-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 71

Inclusion Criteria

• Being women,
• Older than 18 yrs old,
• Not being pregnant,
• Not being disabled,
• For study group; being obese, not for healthy group being systemically health and in normal weight
• Not treated periodontological in the last 6 months

Exclusion Criteria

• Younger than 18 yrs old,
• Smokers who smokes more than 10 cigarettes in a day,
• Uncontrolled systemic diseases,
• Having periodontal treatment
• who needs antibiotic prophylaxis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Obese women	Exercise	Obese women who participated exercise programme.

Primary Outcome Measures

Name	Time	Method
Biochemical variables GCF	12 week	Leptin, adiponectin, resistin concentrations levels (ng/µl)

Secondary Outcome Measures

Name	Time	Method
Biochemical variables_Serum	12 week	leptin, adiponectin, resistin concentrations levels (ng/µl)
Biochemical variables_Saliva	12 week	leptin, adiponectin, resistin concentrations levels (ng/µl)

Trial Locations

Locations (1)

Kocaeli University; 🇹🇷 Kocaeli, Turkey