Comparison of Several Oxygenation Targets With Different Oxygen Interfaces - Impact on Oxygen Flow Rates
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Oxygen Toxicity
- Sponsor
- Laval University
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Oxygen flow
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
Oxygen therapy is at the heart of the healthcare system. Oxygen flow rates depend on a number of confounding factors confounding factors (target used, skin pigmentation, pulse oximeter used, etc.) The investigators have recently have recently demonstrated that the combination of these factors (different peripheral oxygen saturation (SpO2) targets and different oximeters) can have a significant impact on oxygen flows rates. The effect on oxygen flow was not simply additive .
The aim of this study is to evaluate the impact of the interface used on oxygen flow rates in different patient populations (main objective). The investigatoers also evaluate the impact of the interface on carbon dioxide (PaCO2), in particular with closed oxygen masks, with which rebreathing is theoretically possible (secondary objective).
secondary objective).
Investigators
François Lellouche
Principal Investigator
Laval University
Eligibility Criteria
Inclusion Criteria
- •Adult (\> or = 18 years old)
- •Ongoing on conventional oxygen therapy with peripheral oxygen saturation (SpO2) between 88 and 100% with the usual oximeter
- •SpO2 \< 92% ambient air with the usual oximeter
Exclusion Criteria
- •No SpO2 signal with with the usual oximeter
- •False nails or nail polish
- •Severe anemia documented on last blood count during current hospitalization (haemoglobin (Hb) \< 80g/L)
- •Oxygen flow \> 6 L/min
Outcomes
Primary Outcomes
Oxygen flow
Time Frame: Mean Oxygen flow in the five last minute of each study period (between minute 10 and 15)
Oxygen flows (or fraction of inspired oxygen (FiO2)) at the end of each study period (last minute average) to reach peripheral oxygen saturation (SpO2) target to reach SpO2 target with specific oxygen administration interfaces
Secondary Outcomes
- Partial oxygen weaning(Mean oxygen flow in the five last minute of each study period (between minute 10 and 15))
- Complete oxygen weaning(Mean oxygen flow in the five last minute of each study period (between minute 10 and 15))