Influence of Vasculary Inflammation on Development of Diabetes

RWTH Aachen University1 site in 1 country109 target enrollmentJune 2010

ConditionsCoronary Artery Disease(CAD)

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Coronary Artery Disease(CAD)
Sponsor: RWTH Aachen University
Enrollment: 109
Locations: 1
Primary Endpoint: Fat tissue biopsy
Status: Completed
Last Updated: 11 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to investigate if patients with coronary heart disease have higher risk to develop diabetes mellitus among the following two years.

The examination of biomarkers taken from blood and fat issue shall provide which factors could be responsible for development of diabetes mellitus.

Registry

clinicaltrials.gov

Start Date

June 2010

End Date

May 2014

Last Updated

11 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

RWTH Aachen University

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•all patients with MI
•signed informed consent
•older than 18 years
•ability to give informed consent

Exclusion Criteria

•absence of legal competence

Outcomes

Primary Outcomes

Fat tissue biopsy

Time Frame: 2 years

Patients with Coronary artery disease(CAD) undergo a subcutane fat tissue biopsy to identify inflammation and diabetes biomarker, such as TNF, Adiponectin and Clock-Gene. This is done baseline, after 1 year and after 2 years. Comparison of the current measurements among the measurements of the following 2 years shall give evidence about the reasons and conditions of diabetes development.