KCT0001037Completed未知
A double-blind, randomized, parallel, placebo controlled, multi-center phase I/II clinical trial to investigate the safety, tolerability and efficacy of YH14618 following single intradiscal injection in patients with degenerative disc disease
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Yuhan
- Enrollment
- 48
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional Study
Eligibility Criteria
- Ages
- 20(Year) to o Limit (—)
- Sex
- All
Inclusion Criteria
- •1)Degenerative disc disease patients of aged over 20 years
- •2)Appropriate for the study by physical examination, laboratory tests, interview
- •3)Have one or more of the symptomatic lumbar level(L1~S1) as confirmed using radiology(X-ray, MRI and/or discogram/CT)
- •4)Have signed a written informed consent voluntarily, prior to the any procedure
Exclusion Criteria
- •1)Subjects unable to have radiological examination
- •2)Have history of neurological disease
- •3)Sacroiliac joint dysfunction
- •4)Have been treated with any drugs for pain control within 7 days prior to the first administration
- •5)Pregnant women, nursing mothers or subjects who do not agree to assigned contraception in the study
- •6)Participated in any other clinical trials within 30 days prior to the first administration
- •7)Other clinically significant disgnosis not to include by investigator
Investigators
Similar Trials
Withdrawn
Not Applicable
A randomized, parallel, double-blind, placebo controlled trial to investigate HPA-axis activation before and after electro-convulsive therapy in patients with a major depressive episode using an orally administered 5-HTP challenge testdepressiondepressive disorder10027946NL-OMON33643Centre for Human Drug Research30
Active, not recruiting
Not Applicable
A randomized, double blind, parallel, placebo controlled, exploratory study to assess the effect of EA-230 on renal function and on safety and tolerability in patients at increased risk of developing renal failure following major cardiac on-pump surgery.EUCTR2007-007132-25-DEEBI Anti Sepsis B.V.150
Completed
Phase 3
A clinical trial to study the effect of the addition of Vitamin D to conventional treatment in new pulmonary tuberculosis patientsCTRI/2007/091/000008Christian Medical College,Vellore250
Not yet recruiting
Phase 1
Study for Screening of Chinese Patent Drugs in the Rehabilitation Treatment of novel coronavirus pneumonia (COVID-19)ovel coronavirus pneumonia (COVID-19)ITMCTR2000003279Hubei Provincial Hospital of TCM
Completed
Not Applicable
A randomised, double blind, parallel, placebo controlled, drug-drug interaction study to investigate the safety, tolerability and pharmacokinetics of multiple doses of HTL0018318 given alone and in combination with donepezil at steady state in elderly volunteers.dementia & schizophrenia10012272SchizophreniaAlzheimer's diseaseNL-OMON43229Heptares Therapeutics Ltd.36