EUCTR2017-002170-39-FIActive, not recruitingPhase 1
Combination of intrathecal morphine and local infiltration analgesia in treatment postoperative pain of total knee arthroplasty
Eksote0 sites120 target enrollmentStarted: August 16, 2017Last updated:
Conditions
Drugs
Trial Snapshot
- Phase
- Phase 1
- Status
- Active, not recruiting
- Sponsor
- Enrollment
- 120
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional clinical trial of medicinal product
Eligibility Criteria
Inclusion Criteria
- •- 120 patients who have given their written consent
- •- primary total knee arthroplasty
- •- age 18-85 years
- •- ASA I-III
- •- suitable for spinal anesthesia
- •- NSAID not contraindicated
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 40
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range 80
Exclusion Criteria
- •- age <18 or >86 yrs
- •- weight < 50 kgs or BMI =35 kg/m2
- •- ASA IV - V
- •- reoperation
- •- preoperative SpO2 <93%
- •- dementia
- •- drug or alcohol abuse
- •- preoperative use of strong opioids, gabapentin or pregabalin
- •- any drug of the research protocol is contraindicated
Investigators
Similar Trials
Not yet recruiting
Not Applicable
It is randomized controlled trial to know the efficacy of intrathecal morphine combined with 0.75% ropivacaine heavy for postoperative analgesia in laparoscopic cholecystectomy.CTRI/2022/08/045034A
Active, not recruiting
Phase 1
The use of morphine in addition to local anaesthetic for post operative analgesia in anterior cruciate reconstruction - ACL pain trialRupture of anterior cruciate ligament being corrected by anterior cruciate reconstruction.EUCTR2006-002731-24-GBniversity of Aberdeen30
Not yet recruiting
Not Applicable
Comparision of pain after operation for gallbladder cancerwith spinal morphine and epidural analgesiaCTRI/2022/03/040858Department of Oncoanaesthesia and Critical Care SCI
Active, not recruiting
Phase 1
Spinal administration of morphine for laparoscopic pancreatic surgery : A double blind, propspective randomized placebo-controlled trial.postoperative pain treatment after minimally invasive pancreatic surgeryEUCTR2021-002625-20-BEniversity Hospitals Leuven128
Not yet recruiting
Phase 3
Effect of low-dose intrathecal (within the spinal space) morphine as a part of multimodal analgesia (which combines various groups of medications for pain relief) in patients aged 18 to 65 years undergoing cardiac surgery by cutting of breast bone.CTRI/2024/06/068299All India Institute of Medical Sciences