COMPARING THE EFFECTIVENESS OF RAMOSETRON WITH ONDANSETRON IN PREVENTING POSTOPERATIVE NAUSEA AND VOMITING OCCURING AFTER AN OPERATION IN PATIENTS AT A HIGH RISK
Phase 4
Completed
- Conditions
- Health Condition 1: null- Adult Cancer patients undergoing cancer surgery and at a high risk for postoperative nausea and vomiting
- Registration Number
- CTRI/2013/02/003357
- Lead Sponsor
- Tata Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 206
Inclusion Criteria
Adult patients scheduled for breast surgery, parotid surgery, thyroid surgery, gynaecological surgeries.
Aged between 20-60 years
ASA physical status I or II
At a high risk for PONV with at least 2 of the 4 risk factors mentioned below
1 Female patients
2 Non smoking status
3 Past h/o PONV or motion sickness
4 Postoperative opioid use
Exclusion Criteria
1. Pregnant patient
2. Menstruating patients
3. History of GERD
4. Antemetic medication, nausea or vomiting prior to surgery
5. Major intraabdominal,thoracic, pelvic and reconstructive surgeries
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The Incidence of post operative nausea and vomiting (PONV) during the first 24 h after an operationTimepoint: The first 24 h after an operation will be divided into three time intervals 0â??2 , 2â??6 and 6 -24 hours
- Secondary Outcome Measures
Name Time Method The severity of nausea and <br/ ><br>The need for rescue medicationTimepoint: The first 24 h after an operation will be divided into three time intervals 0â??2 , 2â??6 and 6 -24 hours