Detecting mitochondrial oxygen tension (mitoPO2) with the Cellular Oxygen Metabolism (COMET) measurement system as measure of local tissue oxygenation in patients with peripheral arterial disease – A pilot study

niversity Medical Centre Groningen0 个研究点目标入组 20 人开始时间: 待定最近更新: 2024年2月28日

试验速览

暂无简介。

•-Insufficient knowledge of the Dutch language, illiteracy, or language barrier.
•-Lower leg fracture within the past 12 months.
•-(Partial) amputation of one of the feet and/or legs.
•-Tattoos in location of patches.
•-Severe cardiac-pulmonary failure.
•-Known hypersensitivity to the active substance or any of the following excipients: patches: acrylic pressure sensitive adhesive (poly[(2-ethylhexyl)acrylate-co-methylacrylate-co-acrylic acid-co-glycidylmethacrylate]), backing film: pigmented polyethylene aluminium vapor coated polyester, and release liner (polyethylene terephthalate film) which is removed prior to application.
•-Known diagnosis of porphyria.
•-Known photodermatoses of varying pathology and frequency, e.g. metabolic disorders such as aminoaciduria, idiopathic or immunological disorders such as polymorphic light reaction, genetic disorders such as xeroderma pigmentosum, and diseases precipitated or aggravated by exposure to sun light such as lupus erythematoides or phemphigus erythematoides.
•-Diabetes.
•-Previous photodynamic therapy or recent use of a tanning bed.
•-Subjects using medicinal products with known phototoxic or photoallergic potential such as St. John's wort, griseofulvin, thiazide diuretics, sulfonylureas, phenothiazines, sulphonamides, quinolones and tetracyclines.
•-Use of other topical medicinal products.

发起方

niversity Medical Centre Groningen