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Clinical Trials/NL-OMON41866
NL-OMON41866
Not yet recruiting
Not Applicable

*Non-invasive monitoring of mitochondrial oxygen consumption and oxygenation (COMET): observational clinical study.* - Clinical application COMET

Erasmus MC, Universitair Medisch Centrum Rotterdam0 sites45 target enrollmentTBD
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Conditionsbasale fysiologie mitochondriele functieoxygen consumption and oxygenation mitochondrien

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
basale fysiologie mitochondriele functie
Sponsor
Erasmus MC, Universitair Medisch Centrum Rotterdam
Enrollment
45
Status
Not yet recruiting
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Observational non invasive

Investigators

Eligibility Criteria

Inclusion Criteria

  • •\- Age 18\-70 years
  • •\- Acceptable proficiency of the Dutch language
  • •\- ASA 1\-2 patients, in order to limit the influence of co\-morbidities on the mitochondrial function.
  • •\- Surgery for intracranial tumor;besides the inclusion of 40 patients for topical ALA application, we also will include 5 patients who receive ALA (gliolan) systemically for intracranial glioma resection, for further clinical research. In total 45 patients will be included.

Exclusion Criteria

  • •\- allergy 5\-aminolevuline
  • •\- No time to place plaster 3h prior to surgery
  • •\-When there no indication for invasive intra\-arterial blood pressure monitoring
  • •\-Presence of Mitochondrial disease
  • •\- pregnancy/ lactation

Outcomes

Primary Outcomes

Not specified

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