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Endoscopic Measurements of Mitochondrial Oxygen Tension: a pilot study

Completed
Conditions
chronic gastro-intestinal ischemia
lack of oxygen of the intestine
10018031
10003216
Registration Number
NL-OMON42975
Lead Sponsor
Erasmus MC, Universitair Medisch Centrum Rotterdam
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
5
Inclusion Criteria

- * 18 years
- Informed consent
- Unremarkable medical history (no gastroenterologic diseases or surgery, no cardiac or pulmonal diseases)
- No gastrointestinal complaints
- Patent gastrointestinal arteries determined by abdominal echo duplex

Exclusion Criteria

- < 18 years
- unable to give informed consent
- Pregnancy
- Acute or chronic porphyria
- Hypersensitivity for ALA or porphyrin
- Significant stenosis of celiac artery and/or superior mesenteric artery by abdominal echo duplex
- Renal impairment
- Liver impairment

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>To determine the feasibility of the MitoPO2 measurements during upper<br /><br>endoscopy.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>To compare MitoPO2 measurements with VLS measurements.</p><br>
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