on-invasive measurement of mitochondrial oxygenation in patients with Complex Regional Pain Syndrome

Completed

• Conditions: Complex Regional Pain Syndrome; posttraumatic dystrophy; 10034606

• Registration Number: NL-OMON47977
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

• Diagnosed with CRPS according to the new IASP criteria. We will only include
patients that still meet these criteria.
• Clinically the contralateral extremity must be without signs or symptoms in a
way that it can be used as a control
• Signed informed consent

Exclusion Criteria

• < 18 years of age
• Presence of mitochondrial disease
• Porphyria

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Baseline mitoPO2 of the affected and contralateral extremity and MitoVO2 of the<br /><br>affected and contralateral extremity.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>• Demographic parameters such as: age, sex, smoking and consumption of alcohol<br /><br>• General medical history and medication use<br /><br>• CRPS severity score<br /><br>• Videothermography image of the affected and contralateral extremity</p><br>