oninvasive measurement of mitochondrial oxygen tension (mitoPO2) compared to continuous hemoglobin-monitoring during massive hemorrhage in major surgery.
Recruiting
- Conditions
- hemorrhagebloodloss during surgeryblood loss
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
> 18 years of age at start of the study
Planed for elective major surgery (abdominal, orthopaedic and gynaecologic)
with a possible need for blood transfusion.
Exclusion Criteria
* Not able to read or speak Dutch or English
* Skin defects at the measurement side.
* Mentally disabled
* Porphyria
* Presence of mitochondrial disease
* No arterial cannula as standard clinical care during surgery
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Mitochondrial PO2 versus Hb</p><br>
- Secondary Outcome Measures
Name Time Method <p>SpHb, hemoglobin level in blood sampel, hemodynamic and respiratory parameters<br /><br>as they are commonly recorded during general anesthesia.</p><br>