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Clinical Trials/NCT01416168
NCT01416168
Completed
Not Applicable

Pilot Study of a Geriatric Intervention After Colorectal and Lung Cancer Surgery

H. Lee Moffitt Cancer Center and Research Institute1 site in 1 country15 target enrollmentDecember 2008

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Colorectal Cancer
Sponsor
H. Lee Moffitt Cancer Center and Research Institute
Enrollment
15
Locations
1
Primary Endpoint
Feasibility of the Intervention
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

Surgery for colorectal cancer is a major surgery. People above the age of 60 tend to have a higher risk of complications. Some studies indicate that senior cancer patients might benefit from a home support after surgery by a geriatric nurse practitioner and a team, beside their usual post-operative care. The investigators team is planning a large study to assess whether this approach could help patients with colorectal cancer recover better from their surgery, get better cancer treatment after that (e.g. chemotherapy), and possibly live longer. This study you are asked to take part in is a pilot for this large study.

Detailed Description

Our key background data come from the randomized study conducted by McCorkle et al. After evaluation testing, patients will be randomly assigned (similarly to a coin toss) to one of two possible follow-up groups. One would be a regular post-surgery care group (control group), the other will have in addition a support by geriatric nurse practitioner (intervention group). Patients who are assigned to the intervention group: once they arrive home, in addition to their normal post-surgery care, will receive a once a week home visit by a geriatric nurse practitioner (GNP). The GNP will also call the patient once a week in between. The GNP will check any problem patients may have during their recovery and provide or organize care for it. The GNP has a checklist of problems to address so that we can reliably reproduce our intervention in other patients. The GNP will work together with the patient's various doctors and caregivers, as well as a geriatric team. Some of the visits or the telephone calls maybe tape-recorded so that the research team can evaluate the information provided to the patient. We will record any complication patients might have from surgery. No matter which treatment group the patient is assigned to, at the end of a 4 weeks period, we will repeat the tests we did at the beginning to see how they change.

Registry
clinicaltrials.gov
Start Date
December 2008
End Date
November 2013
Last Updated
12 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Colorectal cancer, stage III or IV, confirmed by histology
  • Abdominal surgery by a University of South Florida (USF) surgeon at Moffitt Cancer Center or Tampa General Hospital (TGH)
  • Age 60 years and older
  • Informed consent
  • Living within a one (1) hour radius of Moffitt

Exclusion Criteria

  • Discharge planned to a rehabilitation facility or a nursing home
  • Unable to answer the questionnaires (e.g. because of cognitive impairment, blindness, deafness)
  • Post-operative inpatient stay \>one (1) month

Outcomes

Primary Outcomes

Feasibility of the Intervention

Time Frame: 30 days per participant

The primary end-point for the pilot will be the feasibility of the intervention, measured as follows: * A compliance of \>=90% with the intervention table on page 17 * A success rate (improvement or resolution of problems) of \>= 80% * A completion rate of \>=90% of the initial and final study questionnaires

Secondary Outcomes

  • Whether the Intervention is Faithful to Dr. McCorkle's Original Intervention(30 days per participant)
  • A Successful Collection and Testing of >=90% of the Samples Tested(30 days per participant)
  • Effect Size Estimates for Within-group Changes Between Baseline and 1-month(30 days per participant)

Study Sites (1)

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