Geriatric Intervention in Elderly Surgical Patients With Colorectal Cancer - a Randomized, Controlled Trial.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Colorectal Neoplasms
- Sponsor
- Oslo University Hospital
- Enrollment
- 122
- Locations
- 1
- Primary Endpoint
- Postoperative complications
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
This is a randomized, controlled trial on frail elderly patients (aged 65+) with colorectal cancer. The patients will be randomized into two groups. The control group will receive standard surgical treatment. The intervention group will in addition go through a preoperative comprehensive geriatric assessment. The assessment will include evaluation of co-morbidity and medication, social status, nutritional status, cognition, depression and physical performance. This assessment will form basis of an individualized perioperative intervention.
The main aim of the study is to see if the number of postoperative complications in this group can be reduced by a perioperative geriatric intervention. A study of inflammation markers in serum will also be performed, with focus on identifying potential biological frailty markers.
Investigators
Torgeir Bruun Wyller
Professor
Oslo University Hospital
Eligibility Criteria
Inclusion Criteria
- •Elective surgery for colorectal cancer
Exclusion Criteria
- •Acute surgery
- •Not able to consent
- •Does not consent with registration
Outcomes
Primary Outcomes
Postoperative complications
Time Frame: 30 days after surgery
Secondary Outcomes
- Readmission(30 days after surgery)
- Living at home or in institution(3 months after surgery)
- Length of hospital stay(30 days after surgery)
- Survival(3 months after surgery)
- Reoperation(30 days after surgery)
- Quality of life(3 months after surgery)