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Clinical Trials/CTRI/2018/03/012682
CTRI/2018/03/012682
Not yet recruiting
Phase 3

Comparison of short course antimicrobial therapy vs. conventional antimicrobial therapy in patients with complicated intra-abdominal infections- A randomized control trial

Jawaharlal Institute of PostGraduate Medical Education and Research0 sites0 target enrollmentTBD
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ConditionsHealth Condition 1: null- Complicated Intra-abdominal Infections

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Health Condition 1: null- Complicated Intra-abdominal Infections
Sponsor
Jawaharlal Institute of PostGraduate Medical Education and Research
Status
Not yet recruiting
Last Updated
4 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional

Investigators

Eligibility Criteria

Inclusion Criteria

  • •Patients of complicated intra\-abdominal infections (CIAI) who undergo surgical intervention to achieve adequate source control \+ one or more of the following:
  • •1\. Temperature \<\=36C or \>\= 38 C
  • •2\. WBC count\<\=4000 or \>\= 11,000/mm3
  • •3\. Gastrointestinal dysfunction due to peritonitis, precluding intake of more than half their normal diet (as an indicator of an ileus)

Exclusion Criteria

  • •1\. Non\-perforate, non\-gangrenous appendicitis or cholecystitis
  • •2\. Infected necrotizing pancreatitis.
  • •3\. Primary spontaneous bacterial peritonitis
  • •4\. Infection associated with indwelling peritoneal dialysis catheter
  • •5\.High likelihood of death within 72h\[ Patients in the post operative period who require two ionotropes to maintain hemodynamic stability and are above the age of 65]
  • •6\.Pregnancy
  • •7\.Concurrent infection requiring more than five days of antimicrobial therapy or various antimicrobial regimen.
  • •8\.Patients undergoing planned re\-laparotomy

Outcomes

Primary Outcomes

Not specified

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