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Clinical Trials/NL-OMON46104
NL-OMON46104
Recruiting
Not Applicable

Generation of circulating tumor cell derived organoids through enrichment by leukapheresis - A novel drug screening system in metastatic prostate cancer - Circle study

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
Erasmus MC, Universitair Medisch Centrum Rotterdam
Enrollment
79
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Observational invasive

Investigators

Eligibility Criteria

Inclusion Criteria

  • \- metastasized prostate cancer
  • \- age \* 18 years
  • \- Written informed consent of the patient
  • \- \* 2 adequate peripheral veins as access point for leukapheresis

Exclusion Criteria

  • \- CTC count of \< 5 CTCs/7\.5 mL of blood
  • \- Patients with a known hypersensitivity to the used LA\-anticoagulant
  • \- mHSPC patients with current ADT
  • \- Hemorrhage disease and/or coagulation disorder
  • \- Inadequate liver and/or renal function
  • \- Inadequate hematology and coagulation status
  • \- Chronic viral infections

Outcomes

Primary Outcomes

Not specified

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