NL-OMON46104
Recruiting
Not Applicable
Generation of circulating tumor cell derived organoids through enrichment by leukapheresis - A novel drug screening system in metastatic prostate cancer - Circle study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Erasmus MC, Universitair Medisch Centrum Rotterdam
- Enrollment
- 79
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- metastasized prostate cancer
- •\- age \* 18 years
- •\- Written informed consent of the patient
- •\- \* 2 adequate peripheral veins as access point for leukapheresis
Exclusion Criteria
- •\- CTC count of \< 5 CTCs/7\.5 mL of blood
- •\- Patients with a known hypersensitivity to the used LA\-anticoagulant
- •\- mHSPC patients with current ADT
- •\- Hemorrhage disease and/or coagulation disorder
- •\- Inadequate liver and/or renal function
- •\- Inadequate hematology and coagulation status
- •\- Chronic viral infections
Outcomes
Primary Outcomes
Not specified
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