The Effect of Training on Endothelial Function, Progression of Disease,Inflammation, Heart Rate Variability and Mental Health After Percutaneous Coronary Intervention
- Conditions
- Coronary Artery Disease
- Registration Number
- NCT00469950
- Lead Sponsor
- Helse Stavanger HF
- Brief Summary
The Efector study is an open, randomized and controlled trial assessing the effect of regular exercise training on endothelial function, inflammatory markers, progression of disease, heart rate variability and mental health in patients who have been successfully treated with percutaneous coronary intervention and stent implantation for angina pectoris.
- Detailed Description
Pas er randomized to a 6 months training group or none training. At baseline and at 6 months patients are examined with blood tests to measure serum concentrations of inflammatory markers, a test for endothelial function, heart rate variability and a coronary angiogram. Further patients are asked to answer questionnaires concerning mental health (SF36, HADS).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
- Successful PCI with stent implantation,
- Able to participate in the training program,
- No planned further revascularisation
- CAGB,
- Inflammatory diseases other than CAD,
- Heart failure,
- Severe kidney failure,
- Inability to participate in the training program
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method flow mediated dilation, serum concentrations of biomarkers, restenosis-rate/ late luminal loss, heart rate variability in SDNN 6 months
- Secondary Outcome Measures
Name Time Method Oxygen uptake capacity (mg/kg/min), Sf36 scores 6 months
Trial Locations
- Locations (1)
Stavanger University Hospital
🇳🇴Stavanger, Rogaland, Norway