Effects of Periodontal Therapy on Various Clinical Outcome in Patients with COPD & Severe Chronic Periodontitis
Not Applicable
- Conditions
- Health Condition 1: J449- Chronic obstructive pulmonary disease, unspecified
- Registration Number
- CTRI/2023/07/054960
- Lead Sponsor
- Self
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
oPatients of either sex above 40 years of age
oPatients having >= 20 natural teeth
oPatients with CAL 5mm
oFull Mouth Bleeding score (FMBS)30%.
Exclusion Criteria
oPatients with history of periodontal treatment in last 6 months.
oPatients under long-term antibiotics known to influence periodontal health.
oPatients with chronic systemic inflammatory disease.
oPatients with worsening of respiratory symptoms and expected survival of less than 2 years.
oInability to provide information or to cooperate with the dental examinations.
oPatients with any co-morbidity affecting periodontal health.
oPregnant and lactating patients.
oPatients unable to perform lung function test.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The expected outcomes after periodontal therapy in COPD patients are as following: <br/ ><br>oDecrease in frequency of acute exacerbation and number of hospitalization in COPD patients after periodontal therapy. <br/ ><br>oSignificant change in biomarker levels of TNF-α, hsCRP & IL-1β in COPD patients after periodontal therapy. <br/ ><br>oImproved quality of life after periodontal therapy. <br/ ><br>oImproved lung functions after periodontal therapy. <br/ ><br>Timepoint: The outcomes will be assessed at the end of first year <br/ ><br>
- Secondary Outcome Measures
Name Time Method ilTimepoint: Nil