Exercise effect on patients with multiple sclerosis
- Conditions
- multiple sclerosis.Demyelinating disease of the central nervous system
- Registration Number
- IRCT2015100524370N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
definite diagnosis of MS; the MS patients must have passed at least one year of their diagnosis; patients beable to move and walk; age 18-50 years old; all subjects should be sedentary (less than 2 hours of physical activity during a week); they do not have to orthopedic and any chronic illness that not being able to exercise or have an effect on the cardio-pulmonary system; none of the samples should not take medicines that affect on HR.
Exclusion criteria: dementia; alcohol consumption; pregnancy; relapsing MS in a month to study; pacemaker or any disruptions or other serious cardiovascular and respiratory and orthopedic that prevents people from exercising their maximum limit; beta-blockers consumption.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cardiorespiratory fitness and cardiovascular autonomic contro. Timepoint: Before and 6 weeks after intervention. Method of measurement: cardiopulmonary exercise test.
- Secondary Outcome Measures
Name Time Method The effect of aerobic exercise on fatigue variables. Timepoint: Before and 6 weeks after intervention. Method of measurement: Fatigue questionnaire.;Effects of aerobic training on EDSS variables. Timepoint: Before and 6 weeks after intervention. Method of measurement: Krutze criteria.;The effect of aerobic exercise on respiratory function such as: Vo2/HR, O2 pulse, PETCO2, PETO2, Vd/vt, vt, RR, VE, Vco2 peak RER, VE/VCO2. Timepoint: Before and 6 weeks after intervention. Method of measurement: Cardiopulmonary exercise tes.;The effect of aerobic exercise on walking capacity variables. Timepoint: Before and 6 weeks after intervention. Method of measurement: Questionnaire about physical activity (IPAQ.