The effect of adding the N-acetylcysteine drug to Del Nido's cardioplegia solution on the oxidative stress capacity In patients undergoing coronary artery bypass surgery
Not Applicable
Recruiting
- Conditions
- The protective and antioxidant effect of adding N-acetylcysteine ??to del nido's cardioplegia solution in coronary artery surgeries.subsequent myocardial infarction, type 2I21.A1
- Registration Number
- IRCT20231021059790N1
- Lead Sponsor
- Shahid Rajaei Cardiovascular Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Patient consent to study
study Age over 39 years and under 70 years
No history of sternotomy and heart surgery
Left ventricular ejection fraction greater than 30%
Pulmonary outflow volume with pressure per second (FEV1) greater than 65% in spirometry
Hemoglobin above 10 mg per deciliter
Exclusion Criteria
Need for drug support (receiving inotropes before starting heart surgery)
Having a pacemaker
Having impaired lung function tests for FEV1 less than 40%
Having kidney or liver dysfunction
Pump time more than 120 minutes
Cross clamp less than 45 and more than 100 minutes
Allergy to N-acetylcysteine
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method