EUCTR2006-002744-28-DE进行中（未招募）不适用
Effektivitätsoptimierte und toxizitätsreduzierte Therapie des metastasierten Kolorektalkarzinoms in der First-line Therapie - ERBIMOX
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- iOMEDICO
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- histologically verified colorectal carcinoma with KRAS wildtyp status
- •- no previous chemotherapy of the metastasised colorectal carcinoma (first-line therapy)
- •- at least 1 measurable lesion according to RECIST-criteria
- •- adequate function of liver, kidney and hematopoiesis
- •- written informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •- mutated KRAS expressing colorectal carcinoma
- •- contra-indication against Fluorouracil, Oxaliplatin or Cetuximab
- •- adjuvant therapy with Oxaliplatin up to one year prior to study start
- •- severe neuropathy (CTC-level >2) caused by adjuvant therapy with Oxaliplatin
- •- existant other malignant diseases within the last 5 year (except for: condition after
- •surgery of carcinoma in situ of the uterus or of a basilioma)
- •- existant polyneuropathy
- •- therapeutic radiation or operation within 2 weeky prior to study start
- •- participation in other clinical trials within 4 weeks prior to study start
研究者
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