Urological Injuries During Obstetric and Gynecological Operations

• Conditions: Urologic Injuries

• Registration Number: NCT04162782
• Lead Sponsor: Assiut University

Brief Summary

Iatrogenic urinary tract injuries are more common during obstetric and gynaecological procedures averaging 2.6 per 1000 surgeries . The objective of the study is to estimate the incidence of iatrogenic urinary tract injuries and risk factors during obstetric and gynaecological operations.

Embryologically, the urinary system and genital system have a common origin, so anatomically they are so close that predisposes to iatrogenic trauma to it during obstetric and gynaecological operations. The bladder and distal ureters are the most commonly involved organs. The bladder is a retroperitoneal structure, its trigone rests over the anterior vaginal fornix and the base rests on lower uterine segment and cervix.

Detailed Description

Risk factors may contribute to intra-operative bladder injury - include :

1. Prolonged labour with distended bladder.

2. Obstructed labour.

3. Previous cesarean section.

4. previous myomectomy.

5. previous laparotomy.

6. Cases with possibility of altered anatomy, fibrosis or direct extension of disease process as in cases of chronic pelvic inflammatory disease, endometriosis, and large fibroids especially in the broad ligament, previous pelvic surgery, malignancy, previous irradiation and congenital abnormalities of urogenital system.

7. Past history of uterine perforation, septic abortion.

8. In presence of labour, station of the presenting fetal part deeper than or equal to +1, and a large baby were independent risks for a bladder injury during caesarean section.

9. Well effacement and dilatation of cervix (uterine incision may fall over vagina and dissection of bladder from vagina is difficult in compare to lower uterine segment).

10. Preterm cesarean section where lower segment is not well formed.

11. During cesarean hysterectomy.

12. Rupture uterus may also be combined with bladder injuries.

13. Placenta percreta may penetrate the bladder and cause injury.

Urinary tract injury can be diagnosed intraoperative :

1. presence of urine in the operative field.

2. Hematuria

3. Methylene Blue test

Study Timeline

• Status Verified: 2019-11
• Study First Submitted: 2019-11-12
• Study First Submitted QC: 2019-11-12
• Last Update Submitted: 2019-11-12
• Study First Posted: 2019-11-14
• Last Update Posted: 2019-11-14
• Study Start: 2019-12-01
• Primary Completion: 2020-12-01
• Study Completion: 2021-12-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

• Women that undergo obstetric or gynecological surgery complicated by urinary tract injury
• Aged 15 years or older
• Elective surgeries
• Good performance status

Exclusion Criteria

• Not meeting all of the inclusion criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
frequency of iatrogenic urinary tract injuries during obstetric and gynaecological operations.	one month	frequency of iatrogenic urinary tract injuries during obstetric and gynaecological operations.