Effectiveness of Individualized Homoeopathic Treatment in the Management of Cutaneous Lichen Planus- A Prospective Single-Arm Clinical study

This prospective, open-label, single-arm clinical study is designed to evaluate the effectiveness of individualized homoeopathic treatment in the management of cutaneous lichen planus. The trial will be conducted at Nehru Homoeopathic Medical College & Hospital, New Delhi, with a total of 40 patients aged 18–70 years, diagnosed with cutaneous lichen planus (excluding mucosal involvement), recruited from the outpatient department. Each participant will undergo detailed case-taking, repertorization, and individualized prescription of homoeopathic medicines, administered orally, with dosage and repetition based on symptom severity and patient susceptibility. The duration of the study is 12 months, comprising 6 months of enrollment and 6 months of follow-up. Effectiveness will be assessed primarily through the reduction in disease severity measured by the Lichen Planus Severity Index (LPSI) score, and secondarily by improvement in patient quality of life measured by the Dermatology Life Quality Index (DLQI). Statistical analysis will be performed with significance set at p less than 0.05. Institutional Ethical Committee clearance and CTRI registration will be obtained, informed consent will be taken from all participants, and patient confidentiality and safety will be strictly maintained.