Effect of prune concentrate on blood pressure in subjects with high-normal blood pressure or grade I hypertension: a pilot study.
Not Applicable
- Conditions
- Healthy volunteers Hypertension
- Registration Number
- JPRN-UMIN000020186
- Lead Sponsor
- Hiroshima University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
1) Taking medicines or receiving health guidance for hypertension, diabetes, and/or hyperlipidemia 2) Taking drugs or functional food that may affect the trial 3) Participation in any clinical trial within 90 days of the commencement of the trial 4) Fruit allergy 5) In pregnancy or nursing a child 6) Cardiac, renal, and/or hepatic dysfunction 7) History of severe disease and/or major surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Systolic blood pressure and diastolic blood pressure at baseline, 6 and 12 weeks.
- Secondary Outcome Measures
Name Time Method FMD (flow mediated dilation), NOx, ADMA (asymmetric dimethylarginine), platelet aggregation test, thromboxane B2, urinary 8-isoprostane, MDA (malondialdehyde), urinary 8-OHdG (8-hydroxydeoxyguanosine), BAP (biological antioxident potential) test, high-sensitivity CRP, and intestinal flora (T-RFLP), at baseline and 12 weeks.