Evaluation of Patients With Lupus Nephritis Using Kidney MRI (Magnetic Resonance Imaging)
Trial Snapshot
- Phase
- Not Applicable
- Status
- Terminated
- Sponsor
- Johns Hopkins University
- Enrollment
- 15
- Locations
- 1
- Primary Endpoint
- Presence of inflammation
Study Overview
Brief Summary
This study is being done to find out if a non-invasive Magnetic Resonance Imaging (MRI) examination of the kidneys may be helpful in patients with systemic lupus erythematosus (SLE).
Detailed Description
The primary objective of this research is to evaluate the best techniques for magnetic resonance imaging (MRI) of the kidneys in patients with lupus nephritis. This research is being done to evaluate a minimally-invasive method for assessing kidney inflammation and kidney damage in patients with lupus nephritis. Both kidneys will be assessed.
Study Design
- Study Type
- Observational
- Observational Model
- Other
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Male and female adults over the age of 18 who have been diagnosed with SLE and are able to undergo a kidney MRI.
Exclusion Criteria
- •Any patient that has undergone a renal transplant.
- •Any patient that is receiving renal dialysis
Outcomes
Primary Outcomes
Presence of inflammation
Time Frame: Six months
The presence of inflammation within both kidneys will be measured using MRI.
Presence of fibrosis
Time Frame: Six months
The presence of fibrosis within both kidneys will be measured using MRI.
Secondary Outcomes
No secondary outcomes reported