Study on effects of artichoke in treatment of hypercholesterolemic type 2 diabetic patients

Phase 3

• Conditions: Diabetes mellitus.; Non-insulin-dependent diabetes mellitus

• Registration Number: IRCT201112252288N5
• Lead Sponsor: Jahade Daneshgahi

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Iranian male and female type 2 diabetic outpatients, patients aged 40 to 60 years, patients with fasting serum glucose levels from 150 mg/dl to 200 mg/dl, patients with blood HbA1c levels from 7% to 9% despite taking two 5 mg glyburide tablets and two 500 mg metformin tablets every day, patients using two 5 mg glyburide tablets and two 500 mg metformin tablets every day, patients with fasting serum LDL levels from 100 mg/dl to 150 mg/dl. Exclusion criteria: Patients taking other anti-hyperglycemic and anti-hyperlipidemic agents, patients receiving insulin, patients with cardiac, renal, hepatic, hematological diseases, hypothyroidism, tachycardia, vertigo and seizure, patients with a history of gallstones or gall bladder surgery, patients using estrogen, steroid, beta-blocker and thiazide, pregnant women, women planning pregnancy, breast-feeding women.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fasting glucose serum level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Glycosylated hemoglobin blood level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;LDL serum level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).

Secondary Outcome Measures

Name	Time	Method
SGOT serum level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;SGPT serum level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Total cholesterol serum level. Timepoint: 2 months. Method of measurement: Medical laboratory (Kit).;VLDL serum level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;HDL serum level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Triglyceride serum level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Creatinine serum level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;2 hours postprandial glucose serum level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).